Cause of Restless Legs Syndrome

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The cause of restless legs syndrome is a mystery, though certain types of RLS are associated with a treatable underlying condition.

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RLS overview

RLS Foundation

Though the jury's still out on the cause of restless legs syndrome, the basics of risks, symptoms and treatments are discussed in this straightforward brochure.

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A life with RLS

GlaxoSmithKline

Includes strategies for living with restless legs syndrome, with wellness and nutrition tips. There's also a short section on the cause of restless legs syndrome.

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Discusses what might cause restless legs syndrome. The treatment section includes self-help strategies.

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If not a cause of restless legs syndrome, kidney disease is certainly a risk factor. As this article explains, RLS kidney patients have unique health issues.

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Medications as triggers

Sleep Disorders Guide

While not a direct cause of restless legs syndrome, a certain type of medication can act as a trigger. Discusses how to cope with this complex condition.

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Triggers and tips

RLS Foundation

Caffeine, chocolate or alcohol can be an indirect cause of restless legs syndrome. Certain medications are also triggers. Learn how to cope.

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While the cause of primary restless legs syndrome is still elusive, RLS symptoms can also indicate a treatable condition such as anemia.

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Theories abound

Health A to Z

Altered brain signaling or iron deficiency may be a cause of restless legs syndrome. Drugs that target either problem may improve symptoms.

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An underlying medical condition can also be a cause of restless legs syndrome.

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Though the cause of restless legs syndrome is unknown, an imbalance in a brain signaling protein called dopamine can be a factor.

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Iron in the brain

About: Arthritis

Reduced iron levels in the brain may be a cause of restless legs syndrome, but dietary supplements may not always cure you.

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Brain research

RLS Australia

The brain's inability to process iron can be a cause of restless legs syndrome.

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Two syndrome types

National Sleep Foundation

Learn about the different causes of primary and secondary restless legs syndrome. One possible cause of primary RLS is an iron imbalance in the brain.

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The cause of restless legs syndrome during pregnancy is still unknown, but changing hormone levels may play a role.

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